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Best Southwest American Restaurants in South Side East

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146 restaurants available nearby

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A photo of Chart House Restaurant - Tower of the Americas restaurant
1. Chart House Restaurant - Tower of the Americas
4.2
Awesome(16921)
$$$$
• Mexican • Downtown
Booked 170 times today
Chart House Restaurant - Tower of the Americas in Downtown San Antonio offers an exquisite American dining experience. Renowned for serving up fresh seafood and succulent steaks, the restaurant has been praised for its "absolutely fantastic" cuisine and service that goes "above and beyond." Guests rave about the cedar plank salmon and prime rib, describing their meals as "delicious" and "top tier." The stunning panoramic views from 750 feet in the air make dining here unforgettable. With a rich heritage of over 50 years, Chart House continues to redefine authentic American cuisine, making it a must-visit for both locals and visitors.
A photo of Domingo Restaurante restaurant
2. Domingo Restaurante
4.3
Awesome(1287)
$$$$
• Mexican • Downtown
Booked 109 times today
Join us in our open-air restaurant on the Historic San Antonio River Walk with a natural ambiance where curated contemporary art intersects with a historical setting. Domingo's menus offer the flavors of South Texas and an agave-forward beverage program celebrating the culture of San Antonio with modern culinary flair.
A photo of Bohanan's Prime Steaks and Seafood restaurant
3. Bohanan's Prime Steaks and Seafood
4.8
Exceptional(8657)
$$$$
• Mexican • Downtown
Booked 60 times today
Bohanan's Prime Steaks and Seafood in downtown San Antonio elevates seafood dining to an art form. Known for its "succulent seafood flown in fresh daily," the restaurant ensures that each dish bursts with authentic, ocean-fresh flavors. Diners rave about the "macadamia encrusted red snapper" and "outstanding salmon" that epitomize the exquisite quality of their seafood offerings. The AAA Four Diamond-rated restaurant pairs its seafood with impeccable service, creating an extraordinary dining experience. Located in a historic building near the River Walk, Bohanan's is a must-visit for seafood lovers seeking a memorable meal in a stunning, elegant setting.
A photo of Aleteo restaurant
4. Aleteo
4.3
Awesome(85)
$$$$
• Mexican • Downtown
Booked 45 times today
Perched above the city, Aleteo is a rooftop bar and restaurant that sits beneath a luminous canopy that mirrors the beauty of monarch wings. The menu celebrates a Yucatán fusion of bold regional flavors alongside a curated selection of agave spirits and craft cocktails. Come sunset, Aleteo becomes an effortless setting for mezcal-forward cocktails, music, and easy conversation above the glowing city.
A photo of Bliss Restaurant restaurant
5. Bliss Restaurant
4.9
Exceptional(5211)
$$$$
• Mexican • Downtown
Booked 24 times today
Bliss is consistently among San Antonio’s best restaurants in terms of quality, service and atmosphere. Bliss is located just blocks away from downtown San Antonio in the burgeoning Southtown area. Our mission is to express excellence in the most inclusive, genuine and hospitable way. Bliss serves contemporary American cuisine. Our menu changes frequently with an emphasis on what is seasonal and creative over what is predictable and familiar. Our goal is to create a relaxed yet elegant dining experience in a genuine and comfortable environment.
A photo of Brenner's on the River Walk restaurant
6. Brenner's on the River Walk
4.7
Exceptional(652)
$$$$
• Mexican • Downtown
Booked 27 times today
Brenner's on the River Walk in San Antonio offers a quintessential American dining experience that beautifully marries tradition with elegance. With roots tracing back to 1936, Brenner's is renowned for its commitment to authentic American flavors and exceptional quality. Guests rave about its "phenomenal" dishes, especially the American Wagyu and the delectable bacon-wrapped shrimp. The restaurant's picturesque setting along the River Walk adds to its charm, providing breathtaking views from both indoor and balcony seating. Patrons consistently highlight the "excellent" service, noting that it enhances their dining experience, making Brenner's a must-visit for anyone seeking top-tier American cuisine.
A photo of Biga on the Banks restaurant
Icon
7. Biga on the Banks
4.8
Exceptional(5931)
$$$$
• Mexican • Downtown
Booked 25 times today
Biga on the Banks, located in the heart of Downtown San Antonio, offers an exceptional Dining Bar experience that truly elevates the culinary scene. Overlooking the scenic San Antonio River Walk, it boasts a modern yet inviting ambiance that draws both locals and visitors alike. The menu, crafted by the renowned Bruce Auden, features exquisite dishes like Mahi Mahi and Hill Country Venison. Diners rave about the “fantastic food and great service,” while the eclectic wine list and craft cocktails provide the perfect accompaniment to any meal. With accolades for its consistently high-quality offerings, Biga on the Banks is undoubtedly a "must-go" for anyone seeking an unforgettable dining adventure.
A photo of Landry's Seafood House - San Antonio restaurant
8. Landry's Seafood House - San Antonio
4.4
Awesome(2796)
$$$$
• Mexican • Downtown
Booked 21 times today
Landry's Seafood House in Downtown San Antonio offers an authentic taste of American cuisine with a Gulf Coast flair. Known for its "phenomenal" seafood dishes, this restaurant excels in delivering both quality and flavor, making it a standout destination for American dining. Guests rave about the "exceptional" service, with attentive staff like Ernesto and Crystal enhancing the dining experience. Nestled along the Riverwalk, the ambiance adds to the allure, providing a perfect setting for celebrations. Whether indulging in the melt-in-your-mouth bass or the delectable butter cake, diners leave with a "great experience" that keeps them coming back for more.
A photo of Little Em's Oyster Bar restaurant
9. Little Em's Oyster Bar
4.7
Exceptional(1011)
$$$$
• Mexican • Downtown
Booked 10 times today
Little Em's Oyster Bar in Downtown San Antonio serves up some of the finest American cuisine, with a focus on fresh seafood that truly sets it apart. The restaurant's oysters are a standout, often described as "super delicious & fresh," and they're expertly shucked to perfection. But the culinary delight doesn't stop there; their lobster rolls, celebrated as "always delicious," offer an authentic taste of the American Northeast. With a welcoming atmosphere and attentive service, Little Em's is hailed as a "cute little gem" and the "best fresh-oyster restaurant in San Antonio." It's the perfect spot for a memorable dining experience!
A photo of Ácenar restaurant
10. Ácenar
4.4
Awesome(2695)
$$$$
• Mexican • Downtown
Booked 21 times today
Ácenar in Downtown San Antonio is a true gem for lovers of Fusion and Eclectic cuisine, seamlessly blending contemporary Mexican flavors with Texas regional influences. This innovative culinary hotspot is celebrated for its "culinary explosion of bold Latin-infused flavors," as described by delighted diners. Executive Chef Richard Sánchez crafts dishes that offer a modern twist on traditional favorites, such as seafood enchiladas and sizzling parrilladas, which have been described as "exceptional" and "absolutely delicious." With its hip design and vibrant atmosphere, Ácenar provides a memorable dining experience that stands out on the River Walk, making it a must-visit destination.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • Juan
    1 review
    5.0
    Dined 3 days ago
    When we walked in we were welcomed with a tequila Flight witch was pretty nice , the host was nice and congratulating us on out anniversary witch was wonderful,their tequila selection was out of this world I could be their all day tasting all their tequilas but by that time I would be too drunk , Chef Johnathan was amazing for his recommendations, didn’t have a chance to try every thing on their menu but their tortillas was wonderful, definitely coming back for more , defiantly will recommend to friends a family !!!
    More info
    Mezquite$$$$• Northern Mexican• Downtown
    •
    4.6
  • NarineGold
    Los Angeles •48 reviews
    5.0
    Dined 5 days ago
    Probably the best restaurant on the du walk. Beautiful ambiance and great food.
    More info
    Domingo Restaurante$$$$• Mexican / Southwestern• Downtown
    •
    4.3
  • Francisco
    Houston •1 review
    5.0
    Dined 5 days ago
    My girlfriend had dietary restrictions and the server was very helpful. Shout out to the server. He went and got the chef and he spoke with my girlfriend about what she wanted to order and everything worked out perfectly. That's incredible service!!
    More info
    Ácenar$$$$• Contemporary Mexican• Downtown
    •
    4.4
  • Paul
    New Orleans / Louisiana •3 reviews
    5.0
    Dined on Oct 25, 2025
    Pleasantly surprised by the food and the overall experience. Will definitely go back!
    More info
    Alamo Biscuit Company & Panaderia$$$$• Mexican / Southwestern• Downtown
    •
    3.8
  • MaggieGold
    San Antonio •11 reviews
    5.0
    Dined on Apr 19, 2025
    We arrived late so no opportunity to try any food, but the drinks were fantastic! The view was perfect with the exception that it happened to be extremely windy so ladies be warned. The noise level was perfect we were able to hold a conversation and the ambiance gave a comfortable level of prestige. Would highly recommend.
    More info
    Otro Bar at Canopy by Hilton$$$$• Tapas / Small Plates• Downtown
    •
    4.4

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